Who would benefit from open abdomen in severe acute pancreatitis?-a matched case-control study.

ABSTRACT:

Background

Selection of patients for open abdomen (OA) treatment in severe acute pancreatitis (SAP) is challenging. Treatment related morbidity and risk of adverse events are high; however, refractory abdominal compartment syndrome (ACS) is potentially lethal. Factors influencing the decision to initiate OA treatment are clinically important. We aimed to study these factors to help understand what influences the selection of patients for OA treatment in SAP.

Methods

A single center study of patients with SAP that underwent OA treatment compared with conservatively treated matched controls.

Results

Within study period, 47 patients treated with OA were matched in a 1:1 fashion with conservatively treated control patients. Urinary output under 20 ml/h (OR 5.0 95% CI 1.8-

SUBMITTER: Husu HL 

PROVIDER: S-EPMC8194042 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature