An Interpretable Machine Learning Method for the Detection of Schizophrenia Using EEG Signals.

ABSTRACT: In this work we propose a machine learning (ML) method to aid in the diagnosis of schizophrenia using electroencephalograms (EEGs) as input data. The computational algorithm not only yields a proposal of diagnostic but, even more importantly, it provides additional information that admits clinical interpretation. It is based on an ML model called random forest that operates on connectivity metrics extracted from the EEG signals. Specifically, we use measures of generalized partial directed coherence (GPDC) and direct directed transfer function (dDTF) to construct the input features to the ML model. The latter allows the identification of the most performance-wise relevant features which, in turn, provide some insights about EEG signals and frequency bands that are associated with schizophr

SUBMITTER: Vazquez MA 

PROVIDER: S-EPMC8194273 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature