Structure-based drug repurposing against COVID-19 and emerging infectious diseases: methods, resources and discoveries.

ABSTRACT: To attain promising pharmacotherapies, researchers have applied drug repurposing (DR) techniques to discover the candidate medicines to combat the coronavirus disease 2019 (COVID-19) outbreak. Although many DR approaches have been introduced for treating different diseases, only structure-based DR (SBDR) methods can be employed as the first therapeutic option against the COVID-19 pandemic because they rely on the rudimentary information about the diseases such as the sequence of the severe acute respiratory syndrome coronavirus 2 genome. Hence, to try out new treatments for the disease, the first attempts have been made based on the SBDR methods which seem to be among the proper choices for discovering the potential medications against the emerging and re-emerging infectious diseases. Give

SUBMITTER: Masoudi-Sobhanzadeh Y 

PROVIDER: S-EPMC8194848 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature