Naturally Acquired SARS-CoV-2 Immunity Persists for Up to 11 Months Following Infection.

ABSTRACT:

Background

Characterizing the kinetics of the antibody response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is of critical importance to developing strategies that may mitigate the public health burden of coronavirus disease 2019 (COVID-19). We conducted a prospective, longitudinal analysis of COVID-19 convalescent plasma donors at multiple time points over an 11-month period to determine how circulating antibody levels change over time following natural infection.

Methods

From April 2020 to February 2021, we enrolled 228 donors. At each study visit, subjects either donated plasma or had study samples drawn only. Anti-SARS-CoV-2 donor testing was performed using the VITROS Anti-SARS-CoV-2 Total and IgG assays and an in-house fluorescence reduction neutral

SUBMITTER: De Giorgi V 

PROVIDER: S-EPMC8195007 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature