Longitudinal changes in IgG levels among COVID-19 recovered patients: A prospective cohort study.

ABSTRACT:

Objectives

To quantify SARS-CoV2 IgG antibody titers over time and assess the longevity of the immune response in a multi-ethnic population setting.

Setting

This prospective study was conducted in a tertiary hospital in Abu Dhabi city, UAE, among COVID-19 confirmed patients. The virus-specific IgG were measured quantitatively in serum samples from the patients during three visits over a period of 6 months. Serum IgG levels ≥15 AU/ml was used to define a positive response.

Participants

113 patients were analyzed at first visit, with a mean (SD) age of participants of 45.9 (11.8) years 87.5% of the patients were men. 63 and 27 participants had data available for visits 2 and 3, respectively.

Primary outcome

Change in SARS-CoV2 IgG antibody titers over the visits.

SUBMITTER: Alzaabi AH 

PROVIDER: S-EPMC8195379 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature