Bacteraemia variation during the COVID-19 pandemic; a multi-centre UK secondary care ecological analysis.

ABSTRACT:

Background

We investigated for change in blood stream infections (BSI) with Enterobacterales, coagulase negative staphylococci (CoNS), Streptococcus pneumoniae, and Staphylococcus aureus during the first UK wave of SARS-CoV-2 across five London hospitals.

Methods

A retrospective multicentre ecological analysis was undertaken evaluating all blood cultures taken from adults from 01 April 2017 to 30 April 2020 across five acute hospitals in London. Linear trend analysis and ARIMA models allowing for seasonality were used to look for significant variation.

Results

One hundred nineteen thousand five hundred eighty-four blood cultures were included. At the height of the UK SARS-CoV-2 first wave in April 2020, Enterobacterales bacteraemias were at an historic low across two

SUBMITTER: Denny S 

PROVIDER: S-EPMC8195453 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature