Survival of glioblastoma in relation to tumor location: a statistical tumor atlas of a population-based cohort.

ABSTRACT:

Purpose

Previous studies on the effect of tumor location on overall survival in glioblastoma have found conflicting results. Based on statistical maps, we sought to explore the effect of tumor location on overall survival in a population-based cohort of patients with glioblastoma and IDH wild-type astrocytoma WHO grade II-III with radiological necrosis.

Methods

Patients were divided into three groups based on overall survival: < 6 months, 6-24 months, and > 24 months. Statistical maps exploring differences in tumor location between these three groups were calculated from pre-treatment magnetic resonance imaging scans. Based on the results, multivariable Cox regression analyses were performed to explore the possible independent effect of centrally located tumors compared to k

SUBMITTER: Fyllingen EH 

PROVIDER: S-EPMC8195961 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature