Retrospective study of prognosis of patients with multiple colorectal carcinomas: synchronous versus metachronous makes the difference.

ABSTRACT:

Purpose

Little is known about difference between synchronous colorectal cancer (SCRC) and metachronous colorectal cancer (MCRC) despite the relevance for this selected patient group. The aim of this retrospective review was to analyze patients with SCRC and MCRC.

Methods

All patients who underwent surgery for SCRC and MCRC between 1982 and 2019 were included in this retrospective analysis of our tertiary referral center. Clinical, histological, and molecular genetic characteristics were analyzed. The primary endpoint was cause-specific survival, evaluated by the Kaplan-Meier method. Secondary endpoints were recurrence-free survival and the identification of prognostic factors.

Results

Overall, 3714 patients were included in this analysis. Of those, 3506 (94.4%) had a

SUBMITTER: Barz C 

PROVIDER: S-EPMC8195964 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature