Frailty as a mortality predictor in older adults with COVID-19: A systematic review and meta-analysis of cohort studies.

ABSTRACT: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has caused the coronavirus diseases 2019 (COVID-19) pandemic, continues to spread rapidly worldwide and is associated with high rates of mortality among older adults, those with comorbidities, and those in poor physiological states. This paper aimed to systematically identify the impact of frailty on overall mortality among older adults with COVID-19. We conducted a systematic review of the literature indexed in 4 databases. A random-effects model with inverse variance-weighted meta-analysis using the odds ratio was used to study the association of frailty levels with clinical outcomes among older adults with COVID-19. Heterogeneity was measured using the I² statistic and Egger's test. We identified 22 studi

SUBMITTER: Saragih ID 

PROVIDER: S-EPMC8196304 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature