Temporal Trends in Notification and Mortality of Tuberculosis in China, 2004-2019: A Joinpoint and Age-Period-Cohort Analysis.

ABSTRACT: Tuberculosis (TB) remains a major public health problem in China and worldwide. In this article, we used a joinpoint regression model to calculate the average annual percent change (AAPC) of TB notification and mortality in China from 2004 to 2019. We also used an age-period-cohort (APC) model based on the intrinsic estimator (IE) method to simultaneously distinguish the age, period and cohort effects on TB notification and mortality in China. A statistically downward trend was observed in TB notification and mortality over the period, with AAPCs of -4.2% * (-4.9%, -3.4%) and -5.8% (-7.5%, -4.0%), respectively. A bimodal pattern of the age effect was observed, peaking in the young adult (aged 15-34) and elderly (aged 50-84) groups. More specifically, the TB notification risk populations we

SUBMITTER: Wang L 

PROVIDER: S-EPMC8197385 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature