Exploration of Potential Genetic Biomarkers for Heart Failure: A Systematic Review.

ABSTRACT: Patients with heart failure (HF) often present with signs and symptoms that are often nonspecific and with a wide differential diagnosis, making diagnosis and prognosis of HF by clinical presentation alone challenging. Our knowledge on genetic diversity is rapidly evolving with high-throughput DNA sequencing technology, which makes a great potential for genetic biomarker development. The present review attempts to provide a comprehensive review on the modification of major genetic components in HF patients and to explore the potential application of these components as clinical biomarkers in the diagnosis and in monitoring the progress of HF. The literature search was conducted using six databases, resulting in the inclusion of eighteen studies in the review. The findings of these studies

SUBMITTER: Chair SY 

PROVIDER: S-EPMC8198957 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature