CT-Detected Subsolid Nodules: A Predictor of Lung Cancer Development at Another Location?

ABSTRACT: The purpose of this case-cohort study was to investigate whether the frequency and computed tomography (CT) features of pulmonary nodules posed a risk for the future development of lung cancer (LC) at a different location. Patients scanned between 2004 and 2012 at two Dutch academic hospitals were cross-linked with the Dutch Cancer Registry. All patients who were diagnosed with LC by 2014 and a random selection of LC-free patients were considered. LC patients who were determined to be LC-free at the time of the scan and all LC-free patients with an adequate scan were included. The nodule count and types (solid, part-solid, ground-glass, and perifissural) were recorded per scan. Age, sex, and other CT measures were included to control for confounding factors. The cohort included 163 LC pati

SUBMITTER: Schreuder A 

PROVIDER: S-EPMC8200192 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature