Economic Burden of Multiple Sclerosis in Low- and Middle-Income Countries: A Systematic Review.

ABSTRACT:

Background

Although the economic burden of multiple sclerosis (MS) in high-income countries (HICs) has been extensively studied, information on the costs of MS in low- and middle-income countries (LMICs) remains scarce. Moreover, no review synthesizing and assessing the costs of MS in LMICs has yet been undertaken.

Objective

Our objective was to systematically identify and review the cost of illness (COI) of MS in LMICs to critically appraise the methodologies used, compare cost estimates across countries and by level of disease severity, and examine cost drivers.

Methods

We conducted a systematic literature search for original studies in English, French, and Dutch containing prevalence or incidence-based cost data of MS in LMICs. The search was conducted in MEDLINE (

SUBMITTER: Dahham J 

PROVIDER: S-EPMC8200340 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature