Guidance for the Harmonisation and Improvement of Economic Evaluations of Personalised Medicine.

ABSTRACT:

Objective

The objective of this study was to develop guidance contributing to improved consistency and quality in economic evaluations of personalised medicine (PM), given current ambiguity about how to measure the value of PM as well as considerable variation in the methodology and reporting in economic evaluations of PM.

Methods

A targeted literature review of methodological papers was performed for an overview of modelling challenges in PM. Expert interviews were held to discuss best modelling practice. A systematic literature review of economic evaluations of PM was conducted to gain insight into current modelling practice. The findings were synthesised and used to develop a set of draft recommendations. The draft recommendations were discussed at a stakeholder workshop

SUBMITTER: Vellekoop H 

PROVIDER: S-EPMC8200346 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature