Depression in multiple sclerosis across the adult lifespan.

ABSTRACT:

Objectives

The objective of this study is to examine the burden of depressive symptoms across the adult age span in people with multiple sclerosis (MS) and test if the relationship between depressive symptoms and MS characteristics vary across age groups.

Methods

In analyses of the MS Partners Advancing Technology and Health Solutions (MS PATHS) network of adults with MS, we compared the prevalence of depression in MS PATHS with non-MS controls across age and evaluated for effect modification by age in the association between depressive symptoms and clinical and neuroperformance measures via multivariable-adjusted regression models.

Results

In total, 13,821 individuals with MS were included. The prevalence of depression was higher in MS versus non-MS controls, but was

SUBMITTER: Chan CK 

PROVIDER: S-EPMC8200363 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature