PENTOSAN POLYSULFATE AND VISION: Findings from an International Survey of Exposed Individuals.

ABSTRACT:

Purpose

To investigate patient-reported visual function among individuals taking pentosan polysulfate (PPS) for interstitial cystitis.

Methods

A 27-item online survey was distributed to an international mailing list of individuals with interstitial cystitis in November 2018. Demographic characteristics, PPS exposure history, subjective visual function, and previous macular diagnoses were queried. The impact of PPS use, grouped by tertile of cumulative exposure, on visual function and macular diagnoses was assessed with multivariate logistic regression.

Results

The survey was completed by 912 respondents. Eight hundred and sixty-one (96.4%) were women, and the median age was 55 [interquartile range (IQR), 45-64 years]. Among PPS users, the median exposure was 547.5 g (

SUBMITTER: Uner OE 

PROVIDER: S-EPMC8200367 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature