Impact of Renin-Angiotensin System Blockers on Mortality in Veterans Undergoing Cardiac Surgery.

ABSTRACT: Background Renin-angiotensin system blockers (RASBs) have well-validated benefit in patients with hypertension, coronary artery disease, and left ventricular systolic dysfunction. Their use in the perioperative period, however, has been controversial, including in patients undergoing cardiac surgery, who often have a strong indication for their use. In the current study, we explore the impact of RASB use with 30-day and 1-year mortality after cardiac surgery. Methods and Results The Veterans Affairs Surgical Quality Improvement Program and Corporate Data Warehouse were data sources for this retrospective cohort study. A total of 37 197 veterans undergoing elective coronary artery bypass grafting and or valve repair or replacement over a 10-year period met inclusion criteria and were strati

SUBMITTER: Antoniak DT 

PROVIDER: S-EPMC8200704 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature