Ontology highlight
ABSTRACT:
SUBMITTER: Barreda-Manso MA
PROVIDER: S-EPMC8201247 | biostudies-literature | 2021 Jun
REPOSITORIES: biostudies-literature
Barreda-Manso María Asunción MA Nieto-Díaz Manuel M Soto Altea A Muñoz-Galdeano Teresa T Reigada David D Maza Rodrigo M RM
International journal of molecular sciences 20210605 11
COVID-19 pandemic is caused by betacoronavirus SARS-CoV-2. The genome of this virus is composed of a single strand of RNA with 5' and 3'-UTR flanking a region of protein-coding ORFs closely resembling cells' mRNAs. MicroRNAs are endogenous post-transcriptional regulators that target mRNA to modulate protein expression and mediate cellular functions, including antiviral defense. In the present study, we carried out a bioinformatics screening to search for endogenous human microRNAs targeting the ...[more]