Regional adiposity, cardiorespiratory fitness, and left ventricular strain: an analysis from the Dallas Heart Study.

ABSTRACT:

Background

Low cardiorespiratory fitness (CRF), high body mass index, and excess visceral adiposity are each associated with impairment in left ventricular (LV) peak circumferential strain (E_cc), an intermediate phenotype that precedes the development of clinical heart failure (HF). However, the association of regional fat distribution and CRF with E_cc independent of each other and other potential confounders is not known.

Methods

Participants from the Dallas Heart Study Phase 2 who underwent dual energy X-ray absorptiometry assessment of regional fat distribution, CRF assessment by submaximal treadmill test, and E_cc quantification by tissue-tagged cardiovascular magnetic resonance were included in the analysis. The cross-sectional associatio

SUBMITTER: Kondamudi N 

PROVIDER: S-EPMC8201708 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature