Age and intranasal oxytocin effects on trust-related decisions after breach of trust: Behavioral and brain evidence.

ABSTRACT: Age-related differences in cognition and socioemotional functions, and in associated brain regions, may reduce sensitivity to cues of untrustworthiness, with effects on trust-related decision making and trusting behavior. This study examined age-group differences in brain activity and behavior during a trust game. In this game, participants received "breach-of-trust" feedback after half of the trials. The feedback indicated that only 50% of the monetary investment into their fellow players had resulted in returns. The study also explored the effects of intranasal oxytocin on trust-related decisions in aging, based on suggestions of a modulatory role of oxytocin in response to negative social stimuli and perceptions of trust. Forty-seven younger and 46 older participants self-administered i

SUBMITTER: Frazier I 

PROVIDER: S-EPMC8202094 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature