Persistent Postoperative Opioid Use: A Systematic Literature Search of Definitions and Population-based Cohort Study.

ABSTRACT:

Background

While persistent opioid use after surgery has been the subject of a large number of studies, it is unknown how much variability in the definition of persistent use impacts the reported incidence across studies. The objective was to evaluate the incidence of persistent use estimated with different definitions using a single cohort of postoperative patients, as well as the ability of each definition to identify patients with opioid-related adverse events.

Methods

The literature was reviewed to identify observational studies that evaluated persistent opioid use among opioid-naive patients requiring surgery, and any definitions of persistent opioid use were extracted. Next, the authors performed a population-based cohort study of opioid-naive adults undergoing 1 of 18

SUBMITTER: Jivraj NK 

PROVIDER: S-EPMC8202398 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature