Sensitivity and Specificity of two rapid tests for the diagnosis of infection by Trypanosoma cruzi in a Colombian population.

ABSTRACT:

Objective

To evaluate diagnostic precision of two rapid diagnostic tests (RDT's) on patients with chronic Chagas disease.

Methodology

Prospective study with the following inclusion criteria: subjects older than 3 years, signed informed consent. Exclusion criterion: subjects could not have previously received treatment for infection with T. cruzi. The study population were participants in a screening process undertaken in rural and urban zones of the department Boyacá, Colombia. Two RDT's were performed to all participants: the Chagas Detect Plus InBios (CDP) and the Chagas Stat-Pak (CSP) and as a reference standard the ELISA Chagas III GrupoBios and the Chagas ELISA IgG+IgM I Vircell tests were used. In the case of discordant results between the two ELISA tests, an indirect

SUBMITTER: Suescun-Carrero SH 

PROVIDER: S-EPMC8202949 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature