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Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom.

ABSTRACT: Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcerans strain from a diseased horse in the United Kingdom showing clinical signs of respiratory diphtheria comparable to those seen in people. Our results indicate a role for horses as reservoirs for zoonotic C. ulcerans.

SUBMITTER: Zendri F

PROVIDER: S-EPMC8203807 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Case Report: Toxigenic Corynebacterium ulcerans Diphtheria-Like Infection in a Horse in the United Kingdom.

Zendri Flavia F Isgren Cajsa Marie CM Sinovich Matthew M Richards-Rios Peter P Hopkins Katie L KL Russell Katherine K Groves Natalie N Litt David D Fry Norman K NK Timofte Dorina D

Frontiers in veterinary science 20210601

Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs and cats that have been increasingly involved in zoonotic trasmission. We isolated and characterized, by WGS, a toxigenic C. ulcerans strain from a diseased horse in the United Kingdom showing clinical signs of respiratory diphtheria comparable to those seen in people. Our results indicate a role for horses a ...[more]

PMID: 34141732

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