Quantitative T1 mapping using multi-slice multi-shot inversion recovery EPI.

ABSTRACT: An efficient multi-slice inversion-recovery EPI (MS-IR-EPI) sequence for fast, high spatial resolution, quantitative T₁ mapping is presented, using a segmented simultaneous multi-slice acquisition, combined with slice order shifting across multiple acquisitions. The segmented acquisition minimises the effective TE and readout duration compared to a single-shot EPI scheme, reducing geometric distortions to provide high quality T₁ maps with a narrow point-spread function. The precision and repeatability of MS-IR-EPI T₁ measurements are assessed using both T₁-calibrated and T₂-calibrated ISMRM/NIST phantom spheres at 3 and 7 T and compared with single slice IR and MP2RAGE methods. Magnetization transfer (MT) effects of the spectrally-sele

SUBMITTER: Sanchez Panchuelo RM 

PROVIDER: S-EPMC8204273 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature