Magnitude and determinants of neural tube defect in Africa: a systematic review and meta-analysis.

ABSTRACT:

Background

Neural tube defects (NTDs) are a group of disorders that arise from the failure of the neural tube close between 21 and 28 days after conception. About 90% of neural tube defects and 95% of death due to these defects occurs in low-income countries. Since these NTDs cause considerable morbidity and mortality, this study aimed to determine the prevalence and associated factors of NTDs in Africa.

Methods

The protocol of this study was registered in the International Prospective Register of Systematic Reviews (PROSPERO number: CRD42020149356). All major databases such as PubMed/MEDLINE, EMBASE, CINAHL, Web of Science, African Journals Online (AJOL), and Google Scholar search engine were systematically searched. A random-effect model was used to estimate the pooled pre

SUBMITTER: Atlaw D 

PROVIDER: S-EPMC8204447 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature