Aspergillosis of central nervous system in patients with leukemia and stem cell transplantation: a systematic review of case reports.

ABSTRACT:

Background

Aspergillosis of Central Nervous System (CNS) is a highly lethal infection in patients with leukemia and Stem Cell Transplantation (SCT).

Methods

Case reports of CNS aspergillosis in patients with leukemia and SCT published between 1990 and August 2020 were gathered using a structured search through PubMed/Medline.

Results

Sixty-seven cases were identified over the searches of the PubMed bibliographic database and then, 59 cases were included in the final analysis. Europe had the largest share of cases at 57.6% (34 reports), followed by Americas and Asia. Affected patients were predominantly males (58.6%) and the mean age of the patients was 36.1 years, while 62.7% of the patients were under the age of 50 years. The most common leukemia types include Acute

SUBMITTER: Shariati A 

PROVIDER: S-EPMC8204492 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature