Effect of increased blood flow rate on renal anemia and hepcidin concentration in hemodialysis patients.

ABSTRACT:

Background

Increasing the blood flow rate (BFR) is a useful method for increasing Kt/V and the clearance for low molecular solutes. Hemodialysis patients are often anemic due to hypoerythropoiesis and their chronic inflammatory state. Hepcidin, a hormone that regulates iron homeostasis, is considered as an indicator of iron deficiency in patients with end-stage renal disease. This study aimed to investigate the effects of an increased BFR during hemodialysis on serum hepcidin levels and anemia.

Methods

Between April 2014 and March 2016, 22 chronic dialysis patients (11 men [50.0 %]; mean [± standard deviation] age, 72 ± 12 years) undergoing maintenance hemodialysis treatment, thrice weekly, were enrolled and followed prospectively for 24 months. In April 2014, the BFR was 20

SUBMITTER: Yamamoto M 

PROVIDER: S-EPMC8204539 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature