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A method for the growth of uniform silica shells on different size and morphology upconversion nanoparticles.


ABSTRACT: Lanthanide-doped upconversion nanoparticles have emerged as attractive candidates for biomedical applications. This is due to their excitation and emission wavelengths, which lay the foundation for deeper penetration depth into biological tissue, higher resolution due to reduced scattering and improved imaging contrast as a result of a decrease in autofluorescence background. Usually, their encapsulation within a biocompatible silica shell is a requirement for their dispersion within complex media or for further functionalization of the upconversion nanoparticle surface. However, the creation of a silica shell around upconversion nanoparticles can be often challenging, many times resulting in partial silica coating or nanoparticle aggregation, as well as the production of a large number of

SUBMITTER: Urena-Horno E 

PROVIDER: S-EPMC8204744 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature