Reference Intervals for Serum Thyroid-Stimulating Hormone Based on a Recent Nationwide Cross-Sectional Study and Meta-Analysis.

ABSTRACT:

Objective

The aim of our study was to compare the reference intervals (RIs) [median (2.5^th-97.5^th percentiles)] for thyroid-stimulating hormone (TSH) between subgroups stratified by ethnicity and iodine status in a global context.

Design and methods

Primary data were derived from a recently published cross-sectional study in mainland China. Secondary data were obtained from online databases. The RIs for TSH were calculated in the reference population according to the National Academy of Clinical Biochemistry (NACB) standard and in the disease-free population. A meta-analysis of ethnicity- and iodine status-specific TSH RIs was performed.

Results

The primary data showed that the TSH RI (mU/L) in the disease-free population was 2.33 (0.67, 7.87), w

SUBMITTER: Wang X 

PROVIDER: S-EPMC8204855 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature