Surface adhesion of viruses and bacteria: Defend only and/or vibrationally extinguish also?! A perspective.

ABSTRACT: Coronaviruses COVID-19, SARS-CoV and NL63 use spikes in their corona to bind to angiotensin converting enzyme 2 (ACE2) sites on cytoskeletal membranes of host cells to deliver their viral payload. While groups such as disulfides in ACE2's zinc metallopeptidase, and also in COVID-19's spikes, facilitate such binding, it is worth exploring how similar complementary sites on materials such as polymers, metals, ceramics, fabrics, and biomaterials promote binding of viruses and bacteria and how they could be further engineered to prevent bioactivity, or to act as agents to collect viral payloads in filters or similar devices. In that vein, this article offers a perspective on novel tools and approaches for chemically and topologically modifying most utilitarian surfaces via defensive topologica

SUBMITTER: Kolel-Veetil M 

PROVIDER: S-EPMC8204927 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature