Functional connectivity of the default mode, dorsal attention and fronto-parietal executive control networks in glial tumor patients.

ABSTRACT:

Purpose

Resting state functional magnetic resonance imaging (rsfMRI) is an emerging tool to explore the functional connectivity of different brain regions. We aimed to assess the disruption of functional connectivity of the Default Mode Network (DMN), Dorsal Attention Network(DAN) and Fronto-Parietal Network (FPN) in patients with glial tumors.

Methods

rsfMRI data acquired on 3T-MR of treatment-naive glioma patients prospectively recruited (2015-2019) and matched controls from the 1000 functional-connectomes-project were analyzed using the CONN functional toolbox. Seed-Based Connectivity Analysis (SBCA) and Independent Component Analysis (ICA, with 10 to 100 components) were performed to study reliably the three networks of interest.

Results

35 patients with gliomas (

SUBMITTER: Tordjman M 

PROVIDER: S-EPMC8204932 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature