Age specific recruitment and retention to a large multicentre observational breast cancer trial in older women: The Age Gap Trial.

ABSTRACT:

Introduction

Recruitment and retention are two of the most important factors in successfully running clinical trials. Many trials encounter problems with both, causing delays or preventing study progress. These issues are greater in older adults and patients with cancer.

Materials and methods

We assessed recruitment and retention in a large, multicentre, observational breast cancer study in older female patients (>70 years, N = 3440). Data collected by the Age Gap study were used to assess rates of, and reasons for, patients not being recruited or retained. Statistical analysis assessed the impact of age as a predictor of recruitment and retention.

Results

Between February 2013 and June 2018, 6876 patients were screened and 3456 were consented across 56 United Kingdom

SUBMITTER: Todd A 

PROVIDER: S-EPMC8205116 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature