Immune status changing helps diagnose osteoarticular tuberculosis.

ABSTRACT:

Objective

This study is aimed to develop a new nomogram for the clinical diagnosis of osteoarticular tuberculosis (TB).

Methods

xCell score estimation to obtained the immune cell type abundance scores. We downloaded the expression profile of GSE83456 from GEO and proceed xCell score estimation. The routine blood examinations of 326 patients were collected for further validation. We analyzed univariate and multivariate logistic regression to identified independent predicted factor for developing the nomogram. The performance of the nomogram was assessed using the receiver operating characteristic (ROC) curves. The correlation of ESR with lymphocytes, monocytes, and ML ratio was performed and visualized in osteoarticular TB patients.

Results

Compared with the healthy co

SUBMITTER: Liang T 

PROVIDER: S-EPMC8205131 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature