Hospitalization Rates and Causes Among Persons With HIV in the United States and Canada, 2005-2015.

ABSTRACT:

Background

To assess the possible impact of antiretroviral therapy improvements, aging, and comorbidities, we examined trends in all-cause and cause-specific hospitalization rates among persons with HIV (PWH) from 2005 to 2015.

Methods

In 6 clinical cohorts, we followed PWH in care (≥1 outpatient CD4 count or HIV load [VL] every 12 months) and categorized ICD codes of primary discharge diagnoses using modified Clinical Classifications Software. Poisson regression estimated hospitalization rate ratios for calendar time trends, adjusted for demographics, HIV risk factor, and annually updated age, CD4, and VL.

Results

Among 28 057 patients (125 724 person-years), from 2005 to 2015, the median CD4 increased from 389 to 580 cells/µL and virologic suppression from 55% to 85

SUBMITTER: Davy-Mendez T 

PROVIDER: S-EPMC8205637 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature