Maturational trajectories of non-rapid eye movement slow wave activity and odds ratio product in a population-based sample of youth.

ABSTRACT:

Background

Brain maturation is reflected in the sleep electroencephalogram (EEG) by a decline in non-rapid eye movement (NREM) slow wave activity (SWA) throughout adolescence and a related decrease in sleep depth. However, this trajectory and its sex and pubertal differences lack replication in population-based samples. We tested age-related changes in SWA (0.4-4 Hz) power and odds ratio product (ORP), a standardized measure of sleep depth.

Methods

We analyzed the sleep EEG of 572 subjects aged 6-21 y (48% female, 26% racial/ethnic minority) and 332 subjects 5-12 y followed-up at 12-22 y. Multivariable-adjusted analyses tested age-related cross-sectional and longitudinal trajectories of SWA and ORP.

Results

SWA remained stable from age 6 to 10, decreased between ages

SUBMITTER: Ricci A 

PROVIDER: S-EPMC8206023 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature