Genome and Evolutionary Analysis of Nosema ceranae: A Microsporidian Parasite of Honey Bees.

ABSTRACT: Microsporidia comprise a phylum of single cell, intracellular parasites and represent the earliest diverging branch in the fungal kingdom. The microsporidian parasite Nosema ceranae primarily infects honey bee gut epithelial cells, leading to impaired memory, suppressed host immune responses and colony collapse under certain circumstances. As the genome of N. ceranae is challenging to assembly due to very high genetic diversity and repetitive region, the genome was re-sequenced using long reads. We present a robust 8.8 Mbp genome assembly of 2,280 protein coding genes, including a high number of genes involved in transporting nutrients and energy, as well as drug resistance when compared with sister species Nosema apis. We also describe the loss of the critical protein

SUBMITTER: Huang Q 

PROVIDER: S-EPMC8206274 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature