The establishment of an immunosensor for the detection of SPOP.

ABSTRACT: In this paper, we first synthesis three-dimensional jasmine-like Cu@L-aspartic acid(L-ASP) inorganic-organic hybrid nanoflowers to load palladium-platinum nanoparticles (Pd-Pt NPs) as the signal enhancer in order to quantify intracellular speckle-type POZ domain protein. Scanning electron microscope, fourier transform infrared, energy dispersive spectrometer, X-ray photoelectron spectroscopy analysis was used to characterize the newly synthesized materials. The newly formed Cu@L-Asp/Pd-PtNPs can catalyze the decomposition of hydrogen peroxide and exhibit excellent catalytic performance. When different concentration of speckle-type POZ domain protein is captured by speckle-type POZ domain protein antibody linked to the surface of Cu@L-Asp/Pd-Pt NPs, the current signal decreases with the inc

SUBMITTER: Yue S 

PROVIDER: S-EPMC8206368 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature