Effects of Risperidone in Autistic Children and Young Adults: A Systematic Review and Meta-Analysis.

ABSTRACT: There are several studies investigating the effects of risperidone on autism, but many of these studies are contradictory or inconclusive. This systematic review and meta-analysis investigated the effects of risperidone on five domains of the Aberrant Behaviour Checklist (ABC) scale on Autism Spectrum Disorder (ASD), as well as weight gain and waist circumference. The protocol for the present systematic review and meta-analysis was registered on the International Prospective Register of Systematic Reviews (PROSPERO). For this study, we analysed articles (2,459), selecting them according to the PICOS strategy (Population, Intervention, Comparison, Outcome, Study design). Although risperidone is effective for the treatment of lethargy and inadequate speech, concerns about the association bet

SUBMITTER: Mano-Sousa BJ 

PROVIDER: S-EPMC8206457 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature