Clinical Trials Supporting the Role of the IL-17/IL-23 Axis in Axial Spondyloarthritis.

ABSTRACT: The term spondyloarthritis (SpA) encompasses a heterogeneous group of inflammatory musculoskeletal diseases with several common genetic background and clinical features, including the possible involvement of the axial skeleton with peripheral mono- or oligo- arthritis and frequently coexisting skin, eye and intestinal manifestations. When the sacroiliac joints or other parts of the spine or thoracic wall are predominantly affected at magnetic resonance or X-ray imaging with inflammatory back pain, the disease is classified as axial SpA and the therapeutic choices are significantly different compared to cases of peripheral arthritis. Moving from the narrow effectiveness and safety profiles of non-steroidal anti-inflammatory drugs, there has been a significant research effort aimed at identi

SUBMITTER: Ceribelli A 

PROVIDER: S-EPMC8206811 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature