Acute Treatments for Episodic Migraine in Adults: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Migraine is common and can be associated with significant morbidity, and several treatment options exist for acute therapy.

Objective

To evaluate the benefits and harms associated with acute treatments for episodic migraine in adults.

Data sources

Multiple databases from database inception to February 24, 2021.

Study selection

Randomized clinical trials and systematic reviews that assessed effectiveness or harms of acute therapy for migraine attacks.

Data extraction and synthesis

Independent reviewers selected studies and extracted data. Meta-analysis was performed with the DerSimonian-Laird random-effects model with Hartung-Knapp-Sidik-Jonkman variance correction or by using a fixed-effect model based on the Mantel-Haenszel method if the numb

SUBMITTER: VanderPluym JH 

PROVIDER: S-EPMC8207243 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature