Invasive Management of Coronary Artery Disease in Advanced Renal Disease.

ABSTRACT: Coronary artery disease (CAD) is highly prevalent in chronic kidney disease (CKD). CKD modifies the effects of traditional risk factors on atherosclerosis, with CKD-specific mechanisms, such as inflammation and altered mineral metabolism, playing a dominant pathophysiological role as kidney function declines. Traditional risk models and cardiovascular screening tests perform relatively poorly in the CKD population, and medical treatments including lipid-lowering therapies have reduced efficacy. Clinical presentation of cardiac ischemia in CKD is atypical, whereas invasive therapies are associated with higher rates of complications than in with patients with normal or near normal kidney function. The main focus of the present review is on the invasive approach to management of CAD in late-s

SUBMITTER: Karimi Galougahi K 

PROVIDER: S-EPMC8207307 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature