Long-term cardiac reverse remodeling after cardiac resynchronization therapy.

ABSTRACT:

Introduction

The benefit of cardiac resynchronization therapy (CRT) in heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF) have been observed in the first year. However, there are few data on long-term follow-up and the effect of changes of LVEF on mortality. This study aimed to assess the LV remodeling after CRT implantation and the probable effect of changes in LVEF with repeated measures on mortality over time in a real-world registry.

Methods

Among our cohort of 328 consecutive CRT patients, mixed model effect analysis have been made to describe the temporal evolution of LVEF and LVESV changes over time up with several explanatory variables. Besides, the effect of LVEF along time on the probability of mortality was evaluated using joint mod

SUBMITTER: Alvarez-Alvarez B 

PROVIDER: S-EPMC8207409 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature