A Novel Wearable Device for Motor Recovery of Hand Function in Chronic Stroke Survivors.

ABSTRACT: Background. In monkey, reticulospinal connections to hand and forearm muscles are spontaneously strengthened following corticospinal lesions, likely contributing to recovery of function. In healthy humans, pairing auditory clicks with electrical stimulation of a muscle induces plastic changes in motor pathways (probably including the reticulospinal tract), with features reminiscent of spike-timing dependent plasticity. In this study, we tested whether pairing clicks with muscle stimulation could improve hand function in chronic stroke survivors. Methods. Clicks were delivered via a miniature earpiece; transcutaneous electrical stimuli at motor threshold targeted forearm extensor muscles. A wearable electronic device (WD) allowed patients to receive stimulation at home while p

SUBMITTER: Choudhury S 

PROVIDER: S-EPMC8207486 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature