Genome-wide DNA methylation analysis in Chinese Chenghua and Yorkshire pigs.

ABSTRACT:

Background

The Chinese Chenghua pig (CHP) is a typical Chinese domestic fatty pig breed with superior meat quality characteristics, while the Yorkshire pig (YP) has the characteristics of fast growth and a high rate of lean meat. Long term natural selection and artificial selection resulted in great phenotypic differences between the two breeds, including growth, development, production performance, meat quality, and coat color. However, genome-wide DNA methylation differences between CHP and YP remain unclear.

Results

DNA methylation data were generated for muscle tissues of CHP and YP using reduced representation bisulfite sequencing (RRBS). In this study, a total of 2,416,211 CpG sites were identified. Besides, the genome-wide DNA methylation analysis revealed 722 differe

SUBMITTER: Wang K 

PROVIDER: S-EPMC8207654 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature