The preventive efficacy of vitamin B supplements on the cognitive decline of elderly adults: a systematic review and meta-analysis.

ABSTRACT:

Background

The irreversibility of cognitive impairment of Alzheimer's disease (AD) prompts that preventing or delaying the onset of AD should be a public health priority. Vitamin B supplements can lower the serum homocysteine (Hcy) level, but whether it can prevent cognitive decline or not remains unclear. We aimed to evaluate the preventive efficacy of vitamin B supplements on the cognitive decline of elderly adults.

Methods

We searched PubMed, Embase, The Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, Scopus, Science Direct, PsycINFO from inception to December 1, 2019, and then updated the retrieved results on June 1, 2020. The randomized controlled trials (RCTs) which evaluated the efficacy of vitamin B in mild cognitive impairment (MCI) patient

SUBMITTER: Li S 

PROVIDER: S-EPMC8207668 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature