Large-scale genomic analysis reveals the genetic cost of chicken domestication.

ABSTRACT:

Background

Species domestication is generally characterized by the exploitation of high-impact mutations through processes that involve complex shifting demographics of domesticated species. These include not only inbreeding and artificial selection that may lead to the emergence of evolutionary bottlenecks, but also post-divergence gene flow and introgression. Although domestication potentially affects the occurrence of both desired and undesired mutations, the way wild relatives of domesticated species evolve and how expensive the genetic cost underlying domestication is remain poorly understood. Here, we investigated the demographic history and genetic load of chicken domestication.

Results

We analyzed a dataset comprising over 800 whole genomes from both indigenous chick

SUBMITTER: Wang MS 

PROVIDER: S-EPMC8207802 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature