Prediction of Impending Septic Shock in Children With Sepsis.

ABSTRACT:

Objectives

Sepsis and septic shock are leading causes of in-hospital mortality. Timely treatment is crucial in improving patient outcome, yet treatment delays remain common. Early prediction of those patients with sepsis who will progress to its most severe form, septic shock, can increase the actionable window for interventions. We aim to extend a time-evolving risk score, previously developed in adult patients, to predict pediatric sepsis patients who are likely to develop septic shock before its onset, and to determine whether or not these risk scores stratify into groups with distinct temporal evolution once this prediction is made.

Design

Retrospective cohort study.

Setting

Academic medical center from July 1, 2016, to December 11, 2020.

Patients

Six-thous

SUBMITTER: Liu R 

PROVIDER: S-EPMC8208392 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature