Population-Based Registry Linkages to Improve Validity of Electronic Health Record-Based Cancer Research.

ABSTRACT:

Background

There is tremendous potential to leverage the value gained from integrating electronic health records (EHR) and population-based cancer registry data for research. Registries provide diagnosis details, tumor characteristics, and treatment summaries, while EHRs contain rich clinical detail. A carefully conducted cancer registry linkage may also be used to improve the internal and external validity of inferences made from EHR-based studies.

Methods

We linked the EHRs of a large, multispecialty, mixed-payer health care system with the statewide cancer registry and assessed the validity of our linked population. For internal validity, we identify patients that might be "missed" in a linkage, threatening the internal validity of an EHR study population. For generalizab

SUBMITTER: Thompson CA 

PROVIDER: S-EPMC8208472 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature