Reducing NF-κB Signaling Nutritionally is Associated with Expedited Recovery of Skeletal Muscle Function After Damage.

ABSTRACT:

Context

The early events regulating the remodeling program following skeletal muscle damage are poorly understood.

Objective

The objective of this study was to determine the association between myofibrillar protein synthesis (myoPS) and nuclear factor-kappa B (NF-κB) signaling by nutritionally accelerating the recovery of muscle function following damage.

Design, setting, participants, and interventions

Healthy males and females consumed daily postexercise and prebed protein-polyphenol (PP; n = 9; 4 females) or isocaloric maltodextrin placebo (PLA; n = 9; 3 females) drinks (parallel design) 6 days before and 3 days after 300 unilateral eccentric contractions of the quadriceps during complete dietary control.

Main outcome measures

Muscle function was assessed da

SUBMITTER: Jameson TSO 

PROVIDER: S-EPMC8208676 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature