A teaching tool about the fickle p value and other statistical principles based on real-life data.

ABSTRACT: A poor understanding of statistical analysis has been proposed as a key reason for lack of replicability of many studies in experimental biomedicine. While several authors have demonstrated the fickleness of calculated p values based on simulations, we have experienced that such simulations are difficult to understand for many biomedical scientists and often do not lead to a sound understanding of the role of variability between random samples in statistical analysis. Therefore, we as trainees and trainers in a course of statistics for biomedical scientists have used real data from a large published study to develop a tool that allows scientists to directly experience the fickleness of p values. A tool based on a commonly used software package was developed that allows using random samples

SUBMITTER: Alawbathani S 

PROVIDER: S-EPMC8208928 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature